About the Event

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The mission of the I-YMC-VMeet is to provide an online conference with keynote lectures and flash communication by the most distinguished Italian young scientists who have produced important, break-through discoveries in the last years in Medicinal Chemistry. This idea is aimed to promote networking, gathering young researchers and encouraging discussions on any scientific field related to drug discovery. We strongly believe in the importance of consolidating the interactions of our Community in science and beyond, for this reason we organized a poster session opened to all the members of scientific societies affiliated to EFMC.

Participation, as an author or a visitor, is ABSOLUTELY FREE; simply register here.

To achieve these ambitious goals and expand our community you will be also asked to show/send us something about your hobbies (reading, trips, drink, painting, sport and fashion or whatever talent you have!). Any creative idea will be appreciated and will be helpful to organize some social activities. On behalf of organizing and scientific committees we invite you to join us during this first edition and we look forward to posting your contributions.

Medicinal Chemistry Lectures

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Networking

Roundtable about Medicinal Chemistry Career

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Virtual Social Activities

BEYOND SCIENCE: Medicinal Chemistry Got Talent

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Organizing committee

Giannamaria Annunziato (University of Parma, IT)

Agostino Bruno (Cor.Con. International, IT)

Michele Mari (University of Urbino Carlo Bo, IT)

Alberto Massarotti (University of Piemonte Orientale, IT)

Isabella Romeo (University of Calabria, IT)

Gianluca Sbardella (University of Salerno, IT)

Scientific committee

Giannamaria Annunziato (University of Parma, IT)

Agostino Bruno (Cor.Con. International, IT)

Michele Mari (University of Urbino Carlo Bo, IT)

Alberto Massarotti (University of Piemonte Orientale, IT)

Isabella Romeo (University of Calabria, IT)

Gianluca Sbardella (University of Salerno, IT)

Stefano Alcaro (University of Catanzaro, IT)

Vincenza Andrisano (University of Bologna, IT)

Tiziano Bandiera (IIT, IT)

Violetta Cecchetti (University of Perugia, IT)

Gabriele Costantino (University of Parma, IT)

Patrizia Diana (University of Palermo, IT)

Roberto Di Santo (University of Rome "Sapienza", IT)

Fabrizio Micheli (Aptuit, an Evotec Company, IT)

364

Attendees

20

Speakers

3

Days

66

Posters


Keynote speakers

 

Tiziano Bandiera

IIT, Italy

 

Topic: Market watch: novel drug approvals for 2019

Alfonsina D'Amato

University of Milan, Italy

 

Topic: OMICS profile of SARS-Cov2

Rita Petracca

Marie Sklodowska-Curie Imperial College London, UK

 

Topic: RaPID Selection of Novel Macrocyclic Peptides as Modulators of Rab27a-effector Interactions

Carmine Talarico

Dompé farmaceutici, Italy

 

Topic: The Exscalate4CoV project: how CADD is supporting the fight against SARS-CoV-2. A real journey from HPC to virtual reality


Flash communications

 

Alessandra Altomare

University of Milan, Italy

Samuele Cazzamalli

Philochem, Switzerland

Bruno Cerra

University of Perugia, Italy

Francesco Saverio Di Leva

University of Naples Federico II, Italy

Francesca Morreale

IMP - Research Institute of Molecular Pathology, Austria

Giulia Palermo

University of California Riverside, USA

Alessia Romussi

IFOM - the FIRC Institute of Molecular Oncolology, Italy

Marta Serafini

University of Piemonte Orientale, Italy

Azzurra Stefanucci

University of Chieti-Pescara, Italy

Monica Viviano

University of Salerno, Italy


Roundtable speakers

About Medicinal Chemistry Career

Yves Auberson

(EFMC President) - Novartis, Switzerland

Kristina Goncharenko

(EFMC-YSN) - SpiroChem, Switzerland

Rui Moreira

(EFMC President Elect) - University of Lisbon, Portugal

David Peralta

(Editor-in-Chief, ChemMedChem) - Chemistry Europe, Germany


BEYOND SCIENCE: Medicinal Chemistry Got Talent

In this totally new format of online social event you have the opportunity to show one of your talents beside medicinal chemistry. What is your Talent? It can be Art, Music, Cooking or… whatever you want!

We Just need a Video of a few minutes about Your Talent, the most creative contents will be shown during this special social event to emphasize what the medicinal chemistry community can do… Beyond Science!

For Info about video submitting, Tips and Tricks to Realize your Video, contact: info@i-ymc-vmeet.it


Programme

Wednesday, 22nd July

3:00 - 3:20 pm CET

Opening

3:20 - 3:45 pm CET

Alfonsina D'Amato

University of Milan, Italy

Keynote: OMICS profile of SARS-Cov2

3:45 - 4:00 pm CET

Samuele Cazzamalli

Philochem, Switzerland

Small Molecule-Drug Conjugates: getting small to enhance targeting

4:00 - 4:15 pm CET

Marta Serafini

University of Piemonte Orientale, Italy

Benzimidazoles as IDO1 inhibitors: from a virtual screening to a potential treatment in pancreatic ductal adenocarcinoma

4:15 - 4:30 pm CET

Coffe break

4:30 - 4:55 pm CET

Tiziano Bandiera

IIT, Italy

Keynote: Market watch: novel drug approvals for 2019

4:55 - 5:10 pm CET

Alessandra Altomare

University of Milan, Italy

Analytical strategies for understanding the molecular mechanisms of N-acetyl-cysteine as extracellular antioxidant

5:10 - 5:25 pm CET

Giulia Palermo

University of California Riverside, USA

Aiding the SARS-CoV2 detection through emerging CRISPR-Cas genome editing technologies

5:25 - 5:50 pm CET

Social event

5:50 - 6:00 pm CET

Closing remarks

Thursday, 23rd July

3:00 - 3:05 pm CET

Opening

3:05 - 3:30 pm CET

Carmine Talarico

Dompé farmaceutici, Italy

Keynote: The Exscalate4CoV project: how CADD is supporting the fight against SARS-CoV-2. A real journey from HPC to virtual reality

3:30 - 3:45 pm CET

Francesca Morreale

IMP - Research Institute of Molecular Pathology, Austria

BacPROTACs: bringing the PROTAC approach to the bacterial world

3:45 - 4:00 pm CET

Bruno Cerra

University of Perugia, Italy

Size-tuneable flow synthesis of functional nanoparticles for biomedical applications

4:00 - 4:15 pm CET

Coffe break

4:15 - 4:30 pm CET

Alessia Romussi

IFOM - the FIRC Institute of Molecular Oncolology, Italy

Potent reversible inhibitors of Histone Lysine Demethylase KDM1A/LSD1 efficacious in Acute Myeloid Leukemia models

4:30 - 4:45 pm CET

Monica Viviano

University of Salerno, Italy

Identification of novel pyrazole derivatives as inhibitors of lysine acetyltransferase p300

4:45 - 4:50 pm CET

Medicinal Chemistry Division of the Italian Chemical Society’s Awards

Francesco S. Di Leva

University of Naples Federico II, Italy

Azzurra Stefanucci

University of Chieti-Pescara, Italy

4:50 - 5:05 pm CET

Francesco S. Di Leva

University of Naples Federico II, Italy

Targeting the αvβ6 RGD Integrin: from Computer-Aided Drug Design to Preclinical Applications

5:05 - 5:20 pm CET

Azzurra Stefanucci

University of Chieti-Pescara, Italy

Potent, Efficacious, and Stable Cyclic Opioid Peptides with Long Lasting Antinociceptive Effect after Peripheral Administration

5:20 - 6:00 pm CET

Social event

Friday, 24th July

3:00 - 3:05 pm CET

Opening

3:05 - 3:30 pm CET

Rita Petracca

Marie Sklodowska-Curie Imperial College London, UK

Keynote: RaPID Selection of Novel Macrocyclic Peptides as Modulators of Rab27a-effector Interactions

3:30 - 4:00 pm CET

Poster and Flash prizes

 

 

4:00 - 4:15 pm CET

Coffe break

4:15 - 5:00 pm CET

Round table

About Medicinal Chemistry Career

 

Yves Auberson

(EFMC President) - Novartis, Switzerland

 

Kristina Goncharenko

(EFMC-YSN) - SpiroChem, Switzerland

 

Rui Moreira

(EFMC President Elect) - University of Lisbon, Portugal

 

David Peralta

(Editor-in-Chief, ChemMedChem) - Chemistry Europe, Germany

5:00 - 5:15 pm CET

Closing remarks


Poster session

Poster session will start on Wednesday, July 15 at 11:00 a.m. CET and will finish on Tuesday, July 21 at 11:00 a.m. CET. Winners from the poster session will be announced on Wednesday, July 22 during the symposium and invited to present on Friday, July 24.

Poster prize winners will have the opportunity to present their research talks on the last day of this symposium.

 

Winners

P09 - Vittorio Canale

Department of Medicinal Chemistry, Jagiellonian University Medical College, Poland

Efficient and sustainable synthesis of a potent and selective 5-HT7 receptor antagonist using a mechanochemical approach

P31 - Chiara Lo Caputo

Centre d'Etudes et de Recherche sur le Mdicament de Normandie (CERMN), Francia

Design and synthesis of small molecules to disrupt XIAP/Caspase interaction

P34 - Laura Scalvini

University of Parma, Italia

N-Acylethanolamine Acid Amidase (NAAA): Mechanism of Palmitoylethanolamide Hydrolysis Revealed by Mechanistic Simulations

P42 - Matteo Mori

Department of Pharmaceutical Sciences, University of Milan, Italy

Investigating the inhibition mechanism and catalytic cycle of MbtI, the salicylate synthase from Mycobacterium tuberculosis

P46 - Irene Brusa

University of Bologna Alma Mater Studiorum, Italy

Hit optimization for the development of novel rnf5 inhibitors as therapeutic strategy in cystic fibrosis

P48 - Deborah Palazzotti

University of Perugia, Italy

Small-molecule inhibitors targeting AKT1 active and allosteric sites

P63 - Andreea Larisa Turcu

Universidad de Barcelona, Espaa

A NEW THERAPEUTIC APPROACH FOR ALZHEIMERS DISEASE: NOVEL P2X7 RECEPTOR ANTAGONISTS

P43 - Greta Bagnolini

Italian Institute of Technology-University of Bologna, Italy

Dihydroquinolone pyrazoline-based compound as a new RAD51-BRCA2 protein-protein disruptor to trigger synthetic lethality in pancreatic cancer


Sponsors & Partners

They helping us make this event possible.